The Gly82Ser mutation in AGER contributes to pathogenesis of pulmonary fibrosis in combined pulmonary fibrosis and emphysema (CPFE) in Japanese patients
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-69184-8
Abstract: The dominant pathogenesis underlying the combined pulmonary fibrosis and emphysema (CPFE) remains unresolved. The receptor for advanced glycation end-products (RAGE) is highly expressed in lung tissues and interacts with distinct multiple ligands, implicating it in… read more here.
Keywords: fibrosis; fibrosis emphysema; ager; cpfe ... See more keywords
Abstract 17025: Myeloid Rage Protects From Insulin Resistance in Mice Fed High Fat Diet
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circ.142.suppl_3.17025
Abstract: Introduction: Obesity is a major global health problem, with over one third of adults in the US classified as obese. Obesity often leads to a state of insulin resistance (IR), type 2 diabetes (T2D) and… read more here.
Keywords: mice; body; rage; insulin ... See more keywords
Quantifying archaeo-organic degradation – A multiproxy approach to understand the accelerated deterioration of the ancient organic cultural heritage at the Swedish Mesolithic site Ageröd
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DOI: 10.1371/journal.pone.0239588
Abstract: Despite a growing body of evidence concerning accelerated organic degradation at archaeological sites, there have been few follow-up investigations to examine the status of the remaining archaeological materials in the ground. To address the question… read more here.
Keywords: archaeo organic; organic degradation; swedish mesolithic; site ... See more keywords
MiR-185-3p downregulates advanced glycosylation end product receptor expression and improves renal function in diabetic nephropathy mice.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202005_21193
Abstract: OBJECTIVE To investigate the effects of the downregulation of AGER by miRNA-185-3p on renal function in diabetic nephropathy (DN) mice. MATERIALS AND METHODS Mice were divided into normal, model, NC, miR-185-3p mimic, si-AGER, and miR-185-3p… read more here.
Keywords: mir 185; expression; ager; renal function ... See more keywords
Receptors of Advanced Glycation End Product (RAGE) Suppression Associated With a Preserved Osteogenic Differentiation in Patients With Prediabetes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.799872
Abstract: Type 2 diabetes is widely documented for osteogenic differentiation defect and impaired bone quality, which is related to the skeletal accumulation of advanced glycation end products (AGEs). Prediabetes is a condition in which hyperglycemia is… read more here.
Keywords: ager; osteogenic differentiation; expression; differentiation ... See more keywords