AGEs and neurodegeneration: the Nrf2/glyoxalase-1 interaction
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DOI: 10.18632/oncotarget.14232
Abstract: Advanced glycation endproducts (AGEs) are toxic metabolites deriving from reactions between dicarbonyl compounds, such as methylglyoxal, and proteins, which compromise protein function. AGEs effects are counteracted by an enzymatic cycle where glyoxalase (Glo)-1, the limiting… read more here.
Keywords: glyoxalase; glo; ages neurodegeneration; neurodegeneration ... See more keywords
In Vitro Methodologies to Study the Role of Advanced Glycation End Products (AGEs) in Neurodegeneration
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DOI: 10.3390/nu14020363
Abstract: Advanced glycation end products (AGEs) can be present in food or be endogenously produced in biological systems. Their formation has been associated with chronic neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and… read more here.
Keywords: role; end products; neurodegeneration; glycation end ... See more keywords