Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components
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DOI: 10.1016/j.neuron.2021.03.026
Abstract: Tau aggregates contribute to neurodegenerative diseases, including frontotemporal dementia and Alzheimer's disease (AD). Although RNA promotes tau aggregation in vitro, whether tau aggregates in cells contain RNA is unknown. We demonstrate, in cell culture and mouse… read more here.
Keywords: tau; nuclear speckle; tau aggregates; aggregates rna ... See more keywords