Increased Viability of Sugar Transport-Deficient Mutant of the Periodontal Pathogen, Aggregatibacter actinomycetemcomitans
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DOI: 10.1007/s00284-018-1545-6
Abstract: The periodontal pathogen, Aggregatibacter actinomycetemcomitans is extremely sensitive to even a mildly acidic pH resulting from metabolic acids secreted during growth, losing viability rapidly as the pH goes below 6.0. Cells grown at high glucose… read more here.
Keywords: aggregatibacter actinomycetemcomitans; viability; pathogen aggregatibacter; sugar transport ... See more keywords
Generation of a recombinant Aggregatibacter actinomycetemcomitans RTX toxin in Escherichia coli.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.06.003
Abstract: A leukotoxin (LtxA) that is produced by Aggregatibacter actinomycetemcomitans (Aa) is an important virulence determinant in an aggressive form of periodontitis in adolescents. Understanding the function of this protein at the molecular level is critical… read more here.
Keywords: aggregatibacter actinomycetemcomitans; ltxa; generation; coli ... See more keywords
Influence of culture conditions on porphyrin production in Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis.
Sign Up to like & getrecommendations! Published in 2017 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2016.11.001
Abstract: BACKGROUND Increasing antibiotic resistance among pathogens has raised the demands for new treatment methods such as antimicrobial photodynamic therapy (aPDT) and phototherapy (PT). Experiments for investigating the effects of these methods are often performed in… read more here.
Keywords: aggregatibacter actinomycetemcomitans; actinomycetemcomitans porphyromonas; porphyromonas gingivalis; influence culture ... See more keywords
Real-time quantitative reverse transcription-PCR analysis of expression stability of Aggregatibacter actinomycetemcomitans fimbria-associated gene in response to photodynamic therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2017.02.009
Abstract: BACKGROUND Aggregatibacter actinomycetemcomitans is an etiological agent of both chronic and aggressive periodontitis. Dissemination of A. actinomycetemcomitans from the oral cavity and initiation of systemic infections has led to new approaches for treatment being needed.… read more here.
Keywords: aggregatibacter actinomycetemcomitans; photodynamic therapy; fimbria associated; pcr ... See more keywords
Attenuation of Aggregatibacter actinomycetemcomitans virulence using curcumin-decorated nanophytosomes-mediated photo-sonoantimicrobial chemotherapy
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DOI: 10.1038/s41598-021-85437-6
Abstract: This study aimed to focus on the simultaneous use of antimicrobial photodynamic therapy (aPDT) and sonodynamic antimicrobial chemotherapy (SACT), which is called photo-sonodynamic antimicrobial chemotherapy (PSACT) to attenuate the virulence of Aggregatibacter actinomycetemcomitans. Following the… read more here.
Keywords: chemotherapy; aggregatibacter actinomycetemcomitans; virulence; photo ... See more keywords
The role of Aggregatibacter actinomycetemcomitans and its leukotoxin in periodontitis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Oral Microbiology"
DOI: 10.1080/20002297.2017.1325203
Abstract: ABSTRACT Aggregatibacter actinomycetemcomitans is a Gram-negative periodontitis-associated bacterium that expresses a toxin that selectively affects leukocytes. Leukotoxin is encoded by an operon belonging to the core genome of this bacterial species. Variations in the expression… read more here.
Keywords: aggregatibacter actinomycetemcomitans; aggregatibacter; actinomycetemcomitans leukotoxin; leukotoxin periodontitis ... See more keywords
Peptidoglycan-associated lipoprotein of Aggregatibacter actinomycetemcomitans induces apoptosis and production of proinflammatory cytokines via TLR2 in murine macrophages RAW 264.7 in vitro
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Oral Microbiology"
DOI: 10.1080/20002297.2018.1442079
Abstract: ABSTRACT Peptidoglycan-associated lipoprotein (PAL) is a conserved pro-inflammatory outer membrane lipoprotein in Gram-negative bacteria. Compared to systemic pathogens, little is known about the virulence properties of PAL in Aggregatibacter actinomycetemcomitans (AaPAL). The aims of this… read more here.
Keywords: aggregatibacter actinomycetemcomitans; production; associated lipoprotein; peptidoglycan associated ... See more keywords
Aggregatibacter actinomycetemcomitans LPS binds human interleukin-8
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DOI: 10.1080/20002297.2018.1549931
Abstract: ABSTRACT Various gram-negative species sequester host cytokines using outer membrane proteins or surface modulation by sulfated polysaccharides. An outer membrane lipoprotein (BilRI) of the periodontal pathogen Aggregatibacter actinomycetemcomitans binds several cytokines, including interleukin (IL)-8. Because… read more here.
Keywords: aggregatibacter actinomycetemcomitans; lps binds; outer membrane; binds human ... See more keywords
Interactions between the Aggregatibacter actinomycetemcomitans secretin HofQ and host cytokines indicate a link between natural competence and interleukin-8 uptake
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DOI: 10.1080/21505594.2018.1499378
Abstract: ABSTRACT Naturally competent bacteria acquire DNA from their surroundings to survive in nutrient-poor environments and incorporate DNA into their genomes as new genes for improved survival. The secretin HofQ from the oral pathogen Aggregatibacter actinomycetemcomitans… read more here.
Keywords: aggregatibacter actinomycetemcomitans; competence; interactions aggregatibacter; natural competence ... See more keywords
Aggregatibacter actinomycetemcomitans serotypes associate with periodontal and coronary artery disease status
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Periodontology"
DOI: 10.1111/jcpe.12873
Abstract: AIM We investigated the association between the Aggregatibacter actinomycetemcomitans serotypes, periodontal status and coronary artery disease (CAD). MATERIALS AND METHODS The study population included 497 patients who underwent coronary angiography, and clinical oral examination. Quantitative… read more here.
Keywords: status; aggregatibacter actinomycetemcomitans; serotypes associate; coronary artery ... See more keywords
Comprehensive antimicrobial susceptibility testing of a large collection of clinical strains of Aggregatibacter actinomycetemcomitans does not identify resistance to amoxicillin.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of clinical periodontology"
DOI: 10.1111/jcpe.13148
Abstract: AIM The present study aims to determine the susceptibility of Aggregatibacter actinomycetemcomitans to amoxicillin by investigating a large collection of oral strains of diverse geographical origin. METHODS Two hundred and fifty-seven A. actinomycetemcomitans strains were serotyped… read more here.
Keywords: aggregatibacter actinomycetemcomitans; susceptibility; resistance; large collection ... See more keywords