Inhibition of β-Amyloid Aggregation in Alzheimer’s Disease: The Key Role of (Pro)electrophilic Warheads
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DOI: 10.1021/acsmedchemlett.2c00410
Abstract: Catechols have been largely investigated as antiaggregating agents toward β-amyloid peptide. Herein, as a follow up of a previous series of hydroxycinnamic derivatives, we synthesized a small set of dihydroxy isomers for exploring the role… read more here.
Keywords: inhibition amyloid; role; alzheimer disease; aggregation alzheimer ... See more keywords
Effects of Terahertz Radiation on the Aggregation of Alzheimer’s Aβ42 Peptide
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24055039
Abstract: The pathophysiology of Alzheimer’s disease is thought to be directly linked to the abnormal aggregation of β-amyloid (Aβ) in the nervous system as a common neurodegenerative disease. Consequently, researchers in many areas are actively looking… read more here.
Keywords: aggregation; effects terahertz; terahertz radiation; aggregation alzheimer ... See more keywords