N-Terminus Binding Preference for Either Tanshinone or Analogue in Both Inhibition of Amyloid Aggregation and Disaggregation of Preformed Amyloid Fibrils-Toward Introducing a Kind of Novel Anti-Alzheimer Compounds.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.7b00080
Abstract: Amyloid-β (Aβ40/Aβ42) peptide with a length of 40 or 42 residues is naturally secreted as cleavage product of the amyloid precursor protein, and formation of Aβ aggregates in a patient's brain is a hallmark of… read more here.
Keywords: disaggregation; aggregation; aggregation disaggregation; inhibition ... See more keywords
Assemblies of Increasingly Large Ln-Containing Polyoxoniobates and Intermolecular Aggregation-Disaggregation Interconversions.
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DOI: 10.1021/jacs.2c09546
Abstract: An oxalate-assisted lanthanide (Ln) incorporation strategy is first demonstrated for creating rare high-nuclearity Ln-containing polyoxoniobates (PONbs). With the strategy, a series of high-nuclearity Ln-containing PONbs of 50-nuclearity Dy2Nb48, 103-nuclearity Dy7Nb96, 200-nuclearity Dy10Nb190, and 206-nuclearity Dy14Nb192… read more here.
Keywords: nuclearity; containing polyoxoniobates; aggregation disaggregation; dy10nb190 ... See more keywords
Effect of natural antioxidants on the aggregation and disaggregation of beta-amyloid
Sign Up to like & getrecommendations! Published in 2018 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v16i11.9
Abstract: Purpose : To examine the relationship between higher antioxidant activity and aggregation or disaggregation of beta-amyloid (Aβ) for 21 plants. Methods: Twenty-nine natural plant extracts and their antioxidant activities were analyzed using DPPH assay. The… read more here.
Keywords: disaggregation; aggregation; aggregation disaggregation; antioxidant activities ... See more keywords