Tuning the rate of aggregation of hIAPP into amyloid using small-molecule modulators of assembly
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-022-28660-7
Abstract: Human islet amyloid polypeptide (hIAPP) self-assembles into amyloid fibrils which deposit in pancreatic islets of type 2 diabetes (T2D) patients. Here, we applied chemical kinetics to study the mechanism of amyloid assembly of wild-type hIAPP… read more here.
Keywords: small molecule; hiapp; aggregation; aggregation hiapp ... See more keywords