Investigating the mechanism of action of aggregation-inducing antimicrobial Pept-ins.
Sign Up to like & getrecommendations! Published in 2020 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2020.12.008
Abstract: Aggregation can be selectively induced by aggregation-prone regions (APRs) contained in the target proteins. Aggregation-inducing antimicrobial peptides (Pept-ins) contain sequences homologous to APRs of target proteins and exert their bactericidal effect by causing aggregation of… read more here.
Keywords: inducing antimicrobial; aggregation; pept ins; aggregation inducing ... See more keywords
Construction and comprehensive characterization of an EcLDCc-CatIB set—varying linkers and aggregation inducing tags
Sign Up to like & getrecommendations! Published in 2021 at "Microbial Cell Factories"
DOI: 10.1186/s12934-021-01539-w
Abstract: Background In recent years, the production of inclusion bodies that retained substantial catalytic activity was demonstrated. These catalytically active inclusion bodies (CatIBs) were formed by genetic fusion of an aggregation inducing tag to a gene… read more here.
Keywords: inducing tags; aggregation inducing; linker; catib ... See more keywords