Unfolding and Aggregation Pathways of Variable Domains from Immunoglobulin Light Chains.
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DOI: 10.1021/acs.biochem.2c00704
Abstract: Light chain amyloidosis is the most common form of systemic amyloidosis. This disease is caused by the formation and deposition of amyloid fibers made from immunoglobulin light chains. Environmental conditions such as pH and temperature… read more here.
Keywords: unfolding aggregation; aggregation; aggregation pathways; light chains ... See more keywords
Different Aggregation Pathways and Structures for Aβ40 and Aβ42 Peptides
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DOI: 10.3390/biom11020198
Abstract: Self-aggregation of amyloid-β (Aβ) peptides has been known to play a vital role in the onset stage of neurodegenerative diseases, indicating the necessity of understanding the aggregation process of Aβ peptides. Despite previous studies on… read more here.
Keywords: different aggregation; aggregation; aggregation process; pathways structures ... See more keywords