Taylor dispersion analysis discloses the impairment of Aβ peptide aggregation by the presence of a fluorescent tag
Sign Up to like & getrecommendations! Published in 2022 at "ELECTROPHORESIS"
DOI: 10.1002/elps.202200192
Abstract: The use of fluorescently tagged amyloid peptides, implicated in Alzheimer's disease, to study their aggregation at low concentrations is a common method; however, the fluorescent tag should not introduce a bias in the aggregation process.… read more here.
Keywords: aggregation; dispersion analysis; aggregation process; peptide aggregation ... See more keywords
The effect of β-sheet breaker peptides on metal associated Amyloid-β peptide aggregation process.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2017.05.005
Abstract: Far-UV Circular Dichroism experiments and Atomic Force Microscopy tomography are employed to assess the impact of β-sheet breakers on the Aβ1-40 peptide aggregation process in the presence of Cu2+ or Zn2+ transition metals. In this… read more here.
Keywords: sheet; aggregation; peptide aggregation; aggregation process ... See more keywords
A method to describe energy changes in UV–vis absorbance spectra during the aggregation process of conjugated polymer solutions
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Physics Letters"
DOI: 10.1016/j.cplett.2019.136932
Abstract: Abstract We have defined average photon energy (Eave) to describe energy changes in UV–vis absorbance spectra during the aggregation of conjugated polymer solutions quantitatively. During the aggregation process of P3HS (poly(3-hexylselenophene)), Eave always decreases and… read more here.
Keywords: aggregation; aggregation process; spectra aggregation; energy ... See more keywords
The interaction of nanoparticulate Fe3O4 during the diffusion-limited aggregation process: A molecular dynamics simulation
Sign Up to like & getrecommendations! Published in 2020 at "Powder Technology"
DOI: 10.1016/j.powtec.2020.09.075
Abstract: Abstract Due to the limitations of experimental methods, the study on the aggregation process of nanoparticles is quite insufficient. In this paper, molecular dynamics simulations have been used to investigate the interaction of nanoparticulate Fe3O4… read more here.
Keywords: aggregation; diffusion; molecular dynamics; interaction nanoparticulate ... See more keywords
N-Terminal Acetylation of α-Synuclein Slows down Its Aggregation Process and Alters the Morphology of the Resulting Aggregates
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00104
Abstract: Parkinson’s disease is associated with the aberrant aggregation of α-synuclein. Although the causes of this process are still unclear, post-translational modifications of α-synuclein are likely to play a modulatory role. Since α-synuclein is constitutively N-terminally… read more here.
Keywords: terminal acetylation; aggregation; synuclein; aggregation process ... See more keywords
Fluorescence labeling methods influence the aggregation process of α-syn in vitro differently.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d2nr05487f
Abstract: In a previous study, the coexistence of different aggregation pathways of insulin and β-amyloid (Aβ) peptides was demonstrated by correlative stimulated emission depletion (STED) microscopy and atomic force microscopy (AFM). This had been explained by… read more here.
Keywords: aggregation; aggregation process; microscopy; syn ... See more keywords
Different Aggregation Pathways and Structures for Aβ40 and Aβ42 Peptides
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11020198
Abstract: Self-aggregation of amyloid-β (Aβ) peptides has been known to play a vital role in the onset stage of neurodegenerative diseases, indicating the necessity of understanding the aggregation process of Aβ peptides. Despite previous studies on… read more here.
Keywords: different aggregation; aggregation; aggregation process; pathways structures ... See more keywords