Can aggressive cancers be identified by the “aggressiveness” of their chromatin?
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DOI: 10.1002/bies.202100212
Abstract: Phenotypic plasticity is a crucial feature of aggressive cancer, providing the means for cancer progression. Stochastic changes in tumor cell transcriptional programs increase the chances of survival under any condition. I hypothesize that unstable chromatin… read more here.
Keywords: aggressive cancers; identified aggressiveness; unstable chromatin; cancers identified ... See more keywords
Receptor-Mediated Redox Imbalance: An Emerging Clinical Avenue against Aggressive Cancers
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DOI: 10.3390/biom12121880
Abstract: Cancer cells are more vulnerable to abnormal redox fluctuations due to their imbalanced antioxidant system, where cell surface receptors sense stress and trigger intracellular signal relay. As canonical targets of many targeted therapies, cell receptors… read more here.
Keywords: aggressive cancers; cell; receptor mediated; mediated redox ... See more keywords