Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin binding
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DOI: 10.1172/jci.insight.151583
Abstract: Osteosarcoma (OS) is a lethal disease with few known targeted therapies. Here, we show that decreased ATRX expression is associated with more aggressive tumor cell phenotypes, including increased growth, migration, invasion, and metastasis. These phenotypic… read more here.
Keywords: aggressive features; promotes aggressive; integrin binding; loss ... See more keywords
Are Bethesda III Thyroid Nodules More Aggressive than Bethesda IV Thyroid Nodules When Found to Be Malignant?
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DOI: 10.3390/cancers12092563
Abstract: Simple Summary The Bethesda classification system is a widespread tool used in the initial screening test for thyroid nodules. The system classifies the biopsy of the nodule into 6 categories, each with its associated malignancy… read more here.
Keywords: thyroid nodules; bethesda iii; aggressive features; bethesda ... See more keywords