Phase II study of doxorubicin and thalidomide in patients with refractory aggressive fibromatosis
Sign Up to like & getrecommendations! Published in 2017 at "Investigational New Drugs"
DOI: 10.1007/s10637-017-0542-0
Abstract: SummaryBackground To evaluate the efficacy and safety of doxorubicin (ADM) combined with thalidomide (THA) as a first-line treatment for patients with refractory aggressive fibromatosis (AF). Patients and Methods Eligible patients were treated with ADM 30 mg/m2… read more here.
Keywords: study doxorubicin; refractory aggressive; patients refractory; phase study ... See more keywords
Pazopanib, a promising option for the treatment of aggressive fibromatosis
Sign Up to like & getrecommendations! Published in 2017 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000000474
Abstract: Desmoid tumour/aggressive fibromatosis (DT/AF) is a rare soft-tissue neoplasm that is locally aggressive but does not metastasize. There is no standard systemic treatment for symptomatic patients, although a number of agents are used. Tyrosine kinase… read more here.
Keywords: pazopanib promising; treatment; promising option; aggressive fibromatosis ... See more keywords
Hemorrhagic Shock Caused by an Aggressive Fibromatosis in the Gastropancreatic Region: A Case Report
Sign Up to like & getrecommendations! Published in 2025 at "Case Reports in Oncology"
DOI: 10.1159/000544814
Abstract: Abstract Introduction: Spontaneous tumor lysis syndrome (TLS) is a rare, life-threatening metabolic complication that typically occurs in malignancies with high tumor burden. Early recognition is critical, even in the absence of a known malignancy, to… read more here.
Keywords: report; caused aggressive; shock caused; hemorrhagic shock ... See more keywords
Pediatric recurrent aggressive spinal fibromatosis with progressive kyphosis and neurological deficits
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Orthopaedic Surgery"
DOI: 10.1177/2309499019846618
Abstract: Aggressive fibromatosis is a benign, locally invasive fibroblastic proliferation that can cause compressive effects on adjacent structures. The primary cure of this disease rests in wide excision of the tumor. Unfortunately even when surgical margins… read more here.
Keywords: tumor; neurological deficits; excision; fibromatosis ... See more keywords
Imaging manifestations of cervical aggressive fibromatosis: a case report and literature review
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2024.1458486
Abstract: Cervical aggressive fibromatosis is a rare intermediate tumor characterized by invasive growth. Aggressive fibromatosis (AF), also referred to as desmoid-type fibrosarcoma or grade I fibrosarcoma, is a clonal proliferative lesion of fibroblasts located in deep… read more here.
Keywords: fibromatosis; cervical aggressive; imaging manifestations; aggressive fibromatosis ... See more keywords
Case Report: Gefitinib in EGFR 19del recurrent aggressive fibromatosis
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1537714
Abstract: We present the first case of a male patient with an epidermal growth factor receptor (EGFR) 19del mutation who was diagnosed with intra-abdominal aggressive fibromatosis and familial adenomatous polyposis. We assessed the clinical response of… read more here.
Keywords: report gefitinib; egfr 19del; aggressive fibromatosis; case report ... See more keywords