Periostin silencing suppresses the aggressive phenotype of thyroid carcinoma cells by suppressing the Akt/thyroid stimulating hormone receptor axis
Sign Up to like & getrecommendations! Published in 2017 at "Cytotechnology"
DOI: 10.1007/s10616-017-0141-0
Abstract: Clinical evidence indicates that high periostin expression correlates with aggressive phenotype in thyroid carcinoma. However, the biological roles of periostin in thyroid carcinoma development and progression are still unclear. In this study, we explored the… read more here.
Keywords: periostin; thyroid carcinoma; aggressive phenotype; phenotype thyroid ... See more keywords
Alterations in brain microstructure in rats that develop abnormal aggression following peripubertal stress
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.14061
Abstract: Exposure to early adversity is implicated in the development of aggressive behaviour later in life in some but not all individuals. The reasons for the variability in response to such experiences are not clear but… read more here.
Keywords: peripubertal stress; abnormal aggression; stress; aggressive phenotype ... See more keywords
Abstract 3702: Serine promotes aggressive phenotype in renal cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3702
Abstract: Tumor cells are known to have increased demand for nutrients to support proliferation. Among the most highly utilized nutrients by tumor cells are nonessential amino acids (NEAAs). While the role of NEAAs in supporting tumor… read more here.
Keywords: aggressive phenotype; promotes aggressive; serine promotes; serine ... See more keywords
Effect of ovarian cancer ascites on SKOV-3 cells proteome: new proteins associated with aggressive phenotype in epithelial ovarian cancer
Sign Up to like & getrecommendations! Published in 2018 at "Proteome Science"
DOI: 10.1186/s12953-018-0133-9
Abstract: BackgroundEpithelial ovarian cancer is the second most lethal gynecological cancer worldwide. Ascites can be found in all clinical stages, however in advanced disease stages IIIC and IV it is more frequent and could be massive,… read more here.
Keywords: aggressive phenotype; skov cells; new proteins; ovarian cancer ... See more keywords
Prolactin modulates TNBC aggressive phenotype limiting tumorigenesis.
Sign Up to like & getrecommendations! Published in 2019 at "Endocrine-related cancer"
DOI: 10.1530/erc-18-0523
Abstract: Triple negative breast cancer (TNBC) accounts for ~20% of all breast cancer cases. The management of TNBC represents a challenge due to its aggressive phenotype, heterogeneity and lack of targeted therapy. Loss of cell differentiation… read more here.
Keywords: tumorigenesis; phenotype; breast cancer; aggressive phenotype ... See more keywords
Bile acid and cigarette smoke enhance the aggressive phenotype of esophageal adenocarcinoma cells by downregulation of the mitochondrial uncoupling protein-2
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.22380
Abstract: Limited information is available regarding mechanisms that link the known carcinogenic risk factors of gastro-esophageal reflux and cigarette smoking to metabolic alterations in esophageal adenocarcinoma (EAC). In the present study, we utilized a novel in-vitro… read more here.
Keywords: csc; dca csc; cigarette smoke; aggressive phenotype ... See more keywords
RANTES and IL-6 cooperate in inducing a more aggressive phenotype in breast cancer cells
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DOI: 10.18632/oncotarget.24784
Abstract: Both the CC chemokine ligand 5 (CCL5/RANTES) and interleukin-6 (IL-6), released by mesenchymal stem cells (MSCs) as well as by neoplastic cells, promote breast cancer cell progression through autocrine and paracrine mechanisms. In order to… read more here.
Keywords: aggressive phenotype; phenotype breast; breast; breast cancer ... See more keywords
Non-Canonical WNT5A Signaling Through RYK Contributes to Aggressive Phenotype of the Rheumatoid Fibroblast-Like Synoviocytes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.555245
Abstract: We hypothesized that WNT5A could contribute to the enhanced migration and invasiveness of rheumatoid arthritis fibroblast-like synoviocytes (RA FLS), which is one of the incompletely understood aspects of the RA FLS aggressive phenotype. This hypothesis… read more here.
Keywords: fibroblast like; like synoviocytes; migration; fls ... See more keywords