Early recognition of aggressive pituitary adenomas: a single-centre experience
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-017-3396-5
Abstract: BackgroundPituitary adenomas are usually considered benign tumours, although some of them can exhibit an aggressive behaviour. Patients with clinically aggressive pituitary adenomas are frequently diagnosed with larger masses, and may present an earlier recurrence (or… read more here.
Keywords: adenoma; medical treatment; aggressive pituitary; pituitary adenoma ... See more keywords
Stereotactic reirradiation with temozolomide in patients with recurrent aggressive pituitary tumors and pituitary carcinomas
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-020-03579-5
Abstract: To evaluate the efficacy of a second course of fractionated stereotactic radiotherapy (re-SRT) and temozolomide (TMZ) as salvage treatment option in patients with aggressive pituitary tumors (APTs) and pituitary carcinomas (PCs). Twenty-one patients with recurrent… read more here.
Keywords: stereotactic reirradiation; aggressive pituitary; pituitary carcinomas; year ... See more keywords
Definition and diagnosis of aggressive pituitary tumors
Sign Up to like & getrecommendations! Published in 2019 at "Reviews in Endocrine and Metabolic Disorders"
DOI: 10.1007/s11154-019-09531-x
Abstract: Pituitary adenomas are considered benign tumors, but approximately 10% of them can have an aggressive behavior and more rarely (0.2%) can present metastasis, being classified as pituitary carcinomas. Aggressive adenomas are generally large and invasive… read more here.
Keywords: diagnosis; aggressive pituitary; adenomas; diagnosis aggressive ... See more keywords
Targeted systemic and peptide radio-ligand therapy for aggressive pituitary tumors and carcinomas
Sign Up to like & getrecommendations! Published in 2020 at "Reviews in Endocrine and Metabolic Disorders"
DOI: 10.1007/s11154-020-09554-9
Abstract: Aggressive pituitary tumors comprise a rare but challenging subset of pituitary tumors. A major issue currently is the absence of a holistic definition that reliably identifies these tumors in a prospective manner. Although comprehensive evaluation… read more here.
Keywords: peptide radio; aggressive pituitary; pituitary tumors; therapy ... See more keywords
The journey in diagnosis and treatment, from pituitary adenoma to aggressive pituitary tumors
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DOI: 10.1007/s11154-020-09561-w
Abstract: In this special issue, eminent international experts and collaborators from several continents appraise the present landscape regarding aggressive pituitary tumors, from epidemiology and diagnosis to imaging and specific forms of treatment. Most pituitary adenomas grow… read more here.
Keywords: diagnosis; aggressive pituitary; treatment; pituitary adenomas ... See more keywords
Gamma knife radiosurgery in patients with Cushing’s disease: Comparison of aggressive pituitary corticotroph tumor versus corticotroph adenoma
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2020.106151
Abstract: Aggressive pituitary corticotroph tumors causing Cushing's disease are rare, and there is limited data about their clinical management. Here, we aimed to report our long-term experience with gamma knife radiosurgery (GKRS) as adjuvant treatment in… read more here.
Keywords: cushing disease; aggressive pituitary; pituitary corticotroph; corticotroph tumors ... See more keywords
Multimodal therapy in aggressive pituitary tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Endocrinologia, diabetes y nutricion"
DOI: 10.1016/j.endinu.2019.08.004
Abstract: The concept of aggressive pituitary tumor (APT) has been precisely defined in recent years. These tumors are characterized by morphological (radiological or histopathological) data of invasion, proliferative activity superior to that of typical adenomas and… read more here.
Keywords: therapy aggressive; aggressive pituitary; biology; pituitary tumors ... See more keywords
Aggressive pituitary tumours and pituitary carcinomas
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Endocrinology"
DOI: 10.1038/s41574-021-00550-w
Abstract: Although usually benign, anterior pituitary tumours occasionally exhibit aggressive behaviour, with invasion of surrounding tissues, rapid growth, resistance to conventional treatments and multiple recurrences. In very rare cases, they metastasize and are termed pituitary carcinomas.… read more here.
Keywords: pituitary tumours; aggressive pituitary; pituitary carcinomas; biology ... See more keywords
Dural Invasion as a Marker of Aggressive Pituitary Adenomas
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DOI: 10.1227/neu.0000000000001912
Abstract: BACKGROUND: Predictive markers of aggressive pituitary tumors have not been consistently demonstrated. Dural invasion and invasion-associated proteins, including matrix metalloproteinase-9 (MMP9) and cofilin, have been proposed to predict aggressive behavior and recurrence, but findings to… read more here.
Keywords: aggressive pituitary; expression; invasion; mmp9 cofilin ... See more keywords
Treatment of aggressive pituitary tumours and carcinomas: results of a European Society of Endocrinology (ESE) survey 2016.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of endocrinology"
DOI: 10.1530/eje-17-0933
Abstract: OBJECTIVE To collect outcome data in a large cohort of patients with aggressive pituitary tumours (APT)/carcinomas (PC) and specifically report effects of temozolomide (TMZ) treatment. DESIGN Electronic survey to ESE members Dec 2015-Nov 2016. RESULTS… read more here.
Keywords: response; endocrinology; pituitary tumours; aggressive pituitary ... See more keywords
The Upregulation of Molecules Related to Tumor Immune Escape in Human Pituitary Adenomas
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.726448
Abstract: Human pituitary adenomas are one of the most common intracranial neoplasms. Although most of these tumors are benign and can be treated medically or by transsphenoidal surgery, a subset of these tumors are fast-growing, aggressive,… read more here.
Keywords: immune checkpoint; aggressive pituitary; adenomas; pituitary adenomas ... See more keywords