Path integration in normal aging and Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2021 at "Trends in cognitive sciences"
DOI: 10.1016/j.tics.2021.11.001
Abstract: In this review we discuss converging evidence from human and rodent research demonstrating how path integration (PI) is impaired in healthy aging and Alzheimer's disease (AD), and point to the neural mechanisms that underlie these… read more here.
Keywords: grid cell; path integration; alzheimer disease; aging alzheimer ... See more keywords
Dissociating Normal Aging from Alzheimer’s Disease: A View from Cognitive Neuroscience
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Alzheimer's Disease"
DOI: 10.3233/jad-161099
Abstract: Both normal aging and Alzheimer’s disease (AD) are associated with changes in cognition, grey and white matter volume, white matter integrity, neural activation, functional connectivity, and neurotransmission. Obviously, all of these changes are more pronounced… read more here.
Keywords: dissociating normal; alzheimer disease; aging alzheimer; normal aging ... See more keywords
Progressive attenuation of visual global precedence across healthy aging and Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.893818
Abstract: In the perception of Navon hierarchical stimuli (e.g., large letters made up of small letters), young adults identify large letters faster than small ones (known as ‘global advantage’) and identify more slowly small letters when… read more here.
Keywords: aging alzheimer; alzheimer disease; task; across healthy ... See more keywords
Genome Sequencing Variations in the Octodon degus, an Unconventional Natural Model of Aging and Alzheimer's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.894994
Abstract: The degu (Octodon degus) is a diurnal long-lived rodent that can spontaneously develop molecular and behavioral changes that mirror those seen in human aging. With age some degu, but not all individuals, develop cognitive decline… read more here.
Keywords: aging alzheimer; genome sequencing; disease; alzheimer disease ... See more keywords
Ovarian steroid hormones: A long overlooked but critical contributor to brain aging and Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.948219
Abstract: Ovarian hormones, particularly 17β-estradiol, are involved in numerous neurophysiological and neurochemical processes, including those subserving cognitive function. Estradiol plays a key role in the neurobiology of aging, in part due to extensive interconnectivity of the… read more here.
Keywords: aging alzheimer; brain aging; alzheimer disease; brain ... See more keywords