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Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202506109
Abstract: Aging is the primary risk factor for most neurodegenerative diseases, yet the cell-type-specific progression of brain aging remains poorly understood. Here, we developed human cell-type-specific transcriptomic aging clocks using high-quality single-nucleus RNA sequencing data from…
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Keywords:
type specific;
aging clocks;
brain;
cell ... See more keywords
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Published in 2019 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2019.05.004
Abstract: First published in 2016, predictors of chronological and biological age developed using deep learning (DL) are rapidly gaining popularity in the aging research community. These deep aging clocks can be used in a broad range…
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Keywords:
emergence based;
clocks emergence;
biomarkers aging;
based biomarkers ... See more keywords
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Published in 2025 at "Aging Cell"
DOI: 10.1111/acel.70190
Abstract: Evidence connecting skin aging to functional decline and systemic aging biomarkers is lacking. This study investigated how skin‐aging biomechanics were associated with changes in intrinsic capacity (IC), a marker of healthy aging. We also explored…
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Keywords:
aging clocks;
skin biomechanical;
changes intrinsic;
skin elasticity ... See more keywords
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Published in 2024 at "Science"
DOI: 10.1126/science.adu0711
Abstract: Contest aims to improve molecular assays needed to test aging treatments Contest aims to improve molecular assays needed to test aging treatments
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Keywords:
glory cash;
aging clocks;
science glory;
science ... See more keywords