Loss of Nuclear Envelope Integrity in Aging and Disease.
Sign Up to like & getrecommendations! Published in 2018 at "International review of cell and molecular biology"
DOI: 10.1016/bs.ircmb.2017.07.013
Abstract: The nuclear envelope (NE) serves as a central organizing unit for the eukaryotic cell. By virtue of its highly selective, semipermeable barrier function, the NE shields the enclosed genetic material, while at the same time… read more here.
Keywords: nuclear envelope; integrity; aging disease; loss ... See more keywords
Elastic fibers during aging and disease
Sign Up to like & getrecommendations! Published in 2021 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2021.101255
Abstract: Elastic fibers are essential constituents of the extracellular matrix of higher vertebrates and endow several tissues and organs including lungs, skin and blood vessels with elasticity and resilience. During the human lifespan, elastic fibers are… read more here.
Keywords: fibers aging; elastic fiber; aging disease; elastic fibers ... See more keywords
The effects of aging and disease duration on cognition in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Cognition"
DOI: 10.1016/j.bandc.2020.105650
Abstract: OBJECTIVES Multiple sclerosis (MS) is a disease of the central nervous system that can interfere with cognitive functions. The purpose of this study is to document the impact of MS, aging and disease duration on… read more here.
Keywords: disease; multiple sclerosis; cognition; disease duration ... See more keywords
Telomere Dynamics in Zebrafish Aging and Disease.
Sign Up to like & getrecommendations! Published in 2024 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a041696
Abstract: Fish telomere lengths vary significantly across the numerous species, implicating diverse life strategies and environmental adaptations. Zebrafish have telomere dynamics that are comparable to humans and are emerging as a key model in which to… read more here.
Keywords: disease; aging disease; dynamics zebrafish; zebrafish aging ... See more keywords
Is Aging a Disease?
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.70535
Abstract: In the fall, the World Health Organization will review the revisions to the eleventh “International Statistical Classification of Disease and Related Health Problems” (ICD-11), and while the title alone can lull you to sleep, it… read more here.
Keywords: health; disease; aging disease; dermatology ... See more keywords
Simulating impaired left ventricular–arterial coupling in aging and disease: a systematic review
Sign Up to like & getrecommendations! Published in 2024 at "BioMedical Engineering OnLine"
DOI: 10.1186/s12938-024-01206-2
Abstract: Aortic stenosis, hypertension, and left ventricular hypertrophy often coexist in the elderly, causing a detrimental mismatch in coupling between the heart and vasculature known as ventricular−vascular (VA) coupling. Impaired left VA coupling, a critical aspect… read more here.
Keywords: aging disease; review; heart; systematic review ... See more keywords
Vascular Stiffness in Aging and Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.762437
Abstract: The goal of this review is to provide further understanding of increased vascular stiffness with aging, and how it contributes to the adverse effects of major human diseases. Differences in stiffness down the aortic tree… read more here.
Keywords: aging disease; vascular stiffness; stiffness; research ... See more keywords
Effects of Aging and Disease Conditions in Brain of Tumor-Bearing Mice: Evaluation of Purine DNA Damages and Fatty Acid Pool Changes
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12081075
Abstract: The consequences of aging and disease conditions in tissues involve reactive oxygen species (ROS) and related molecular alterations of different cellular compartments. We compared a murine model of immunodeficient (SCID) xenografted young (4 weeks old)… read more here.
Keywords: disease conditions; dna; aging disease; brain ... See more keywords
The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10020490
Abstract: Mitochondria are intracellular organelles that utilize nutrients to generate energy in the form of ATP by oxidative phosphorylation. Mitochondrial DNA (mtDNA) in humans is a 16,569 base pair double-stranded circular DNA that encodes for 13… read more here.
Keywords: dna; aging disease; mitochondrial dna; mitochondrial genome ... See more keywords
Mitochondrial Dysfunction and Oxidative Stress in Aging and Disease
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10112872
Abstract: Mitochondria are considered to have a significant influence on aging due to their critical role in the regulation of bioenergetics, oxidative stress, and cell death [...]. read more here.
Keywords: stress; stress aging; aging disease; oxidative stress ... See more keywords
Special Issue “Polyamines in Aging and Disease”
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252211960
Abstract: Polyamines are bioactive amines found in almost all living organisms and are essential for normal cellular functions [...]. read more here.
Keywords: issue polyamines; special issue; aging disease; polyamines aging ... See more keywords