Loss of Nuclear Envelope Integrity in Aging and Disease.
Sign Up to like & getrecommendations! Published in 2018 at "International review of cell and molecular biology"
DOI: 10.1016/bs.ircmb.2017.07.013
Abstract: The nuclear envelope (NE) serves as a central organizing unit for the eukaryotic cell. By virtue of its highly selective, semipermeable barrier function, the NE shields the enclosed genetic material, while at the same time… read more here.
Keywords: nuclear envelope; integrity; aging disease; loss ... See more keywords
Elastic fibers during aging and disease
Sign Up to like & getrecommendations! Published in 2021 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2021.101255
Abstract: Elastic fibers are essential constituents of the extracellular matrix of higher vertebrates and endow several tissues and organs including lungs, skin and blood vessels with elasticity and resilience. During the human lifespan, elastic fibers are… read more here.
Keywords: fibers aging; elastic fiber; aging disease; elastic fibers ... See more keywords
The effects of aging and disease duration on cognition in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Cognition"
DOI: 10.1016/j.bandc.2020.105650
Abstract: OBJECTIVES Multiple sclerosis (MS) is a disease of the central nervous system that can interfere with cognitive functions. The purpose of this study is to document the impact of MS, aging and disease duration on… read more here.
Keywords: disease; multiple sclerosis; cognition; disease duration ... See more keywords
Vascular Stiffness in Aging and Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.762437
Abstract: The goal of this review is to provide further understanding of increased vascular stiffness with aging, and how it contributes to the adverse effects of major human diseases. Differences in stiffness down the aortic tree… read more here.
Keywords: aging disease; vascular stiffness; stiffness; research ... See more keywords
Effects of Aging and Disease Conditions in Brain of Tumor-Bearing Mice: Evaluation of Purine DNA Damages and Fatty Acid Pool Changes
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12081075
Abstract: The consequences of aging and disease conditions in tissues involve reactive oxygen species (ROS) and related molecular alterations of different cellular compartments. We compared a murine model of immunodeficient (SCID) xenografted young (4 weeks old)… read more here.
Keywords: disease conditions; dna; aging disease; brain ... See more keywords
The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10020490
Abstract: Mitochondria are intracellular organelles that utilize nutrients to generate energy in the form of ATP by oxidative phosphorylation. Mitochondrial DNA (mtDNA) in humans is a 16,569 base pair double-stranded circular DNA that encodes for 13… read more here.
Keywords: dna; aging disease; mitochondrial dna; mitochondrial genome ... See more keywords
Mitochondrial Dysfunction and Oxidative Stress in Aging and Disease
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10112872
Abstract: Mitochondria are considered to have a significant influence on aging due to their critical role in the regulation of bioenergetics, oxidative stress, and cell death [...]. read more here.
Keywords: stress; stress aging; aging disease; oxidative stress ... See more keywords