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   Articles with "aging drosophila" as a keyword



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Germline stem cell aging in the Drosophila ovary.

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recommendations! Published in 2020 at "Current opinion in insect science"

DOI: 10.1016/j.cois.2019.11.003

Abstract: The age-related decline of adult stem cells leads to loss of tissue homeostasis and contributes to organismal aging. Though the phenotypic hallmarks of aging are well-characterized at the organ or tissue level, the molecular processes… read more here.

Keywords: drosophila ovary; stem cell; aging drosophila; cell aging ... See more keywords
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Expression patterns of cardiac aging in Drosophila

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recommendations! Published in 2017 at "Aging Cell"

DOI: 10.1111/acel.12559

Abstract: Aging causes cardiac dysfunction, often leading to heart failure and death. The molecular basis of age‐associated changes in cardiac structure and function is largely unknown. The fruit fly, Drosophila melanogaster, is well‐suited to investigate the… read more here.

Keywords: heart; cardiac aging; expression patterns; patterns cardiac ... See more keywords
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Transposable element landscapes in aging Drosophila

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recommendations! Published in 2022 at "PLoS Genetics"

DOI: 10.1371/journal.pgen.1010024

Abstract: Genetic mechanisms that repress transposable elements (TEs) in young animals decline during aging, as reflected by increased TE expression in aged animals. Does increased TE expression during aging lead to more genomic TE copies in… read more here.

Keywords: element landscapes; aging drosophila; transposable element; drosophila ... See more keywords
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Obesity and Aging in the Drosophila Model

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recommendations! Published in 2018 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms19071896

Abstract: Being overweight increases the risk of many metabolic disorders, but how it affects lifespan is not completely clear. Not all obese people become ill, and the exact mechanism that turns excessive fat storage into a… read more here.

Keywords: drosophila model; model; obesity aging; obesity ... See more keywords