Targeting chromatin aging - The epigenetic impact of longevity-associated interventions
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2016.12.010
Abstract: A rapidly growing body of evidence has shown that chromatin undergoes radical alterations as an organism ages, but how these changes relate to aging itself is an open question. It is likely that these processes… read more here.
Keywords: longevity; chromatin; impact; chromatin aging ... See more keywords
Epigenetic clock and methylation study of oocytes from a bovine model of reproductive aging
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DOI: 10.1111/acel.13349
Abstract: Cattle are an attractive animal model of fertility in women due to their high degree of similarity relative to follicle selection, embryo cleavage, blastocyst formation, and gestation length. To facilitate future studies of the epigenetic… read more here.
Keywords: methylation; aging epigenetic; model; reproductive aging ... See more keywords
Breaking the aging epigenetic barrier
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.943519
Abstract: Aging is an inexorable event occurring universally for all organisms characterized by the progressive loss of cell function. However, less is known about the key events occurring inside the nucleus in the process of aging.… read more here.
Keywords: breaking aging; epigenetic barrier; aging epigenetic; biology ... See more keywords