Novel biomarkers for the evaluation of aging-induced proteinopathies
Sign Up to like & getrecommendations! Published in 2020 at "Biogerontology"
DOI: 10.1007/s10522-020-09878-8
Abstract: Proteinopathies are characterized by aging related accumulation of misfolded protein aggregates. Irreversible covalent modifications of aging proteins may significantly affect the native three dimentional conformation of proteins, alter their function and lead to accumulation of… read more here.
Keywords: accumulation; aging induced; biomarkers evaluation; induced proteinopathies ... See more keywords
Daily behavioral and sleep patterns are associated with aging-induced male-specific disorders in individuals with reduced renal function
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2022.111717
Abstract: BACKGROUND The development of aging-induced male-specific disorders is accelerated by impaired renal function. Although aging-induced male-specific disorders are clinically serious complications in individuals with reduced renal function, their practical management strategies remain obscure. The purpose… read more here.
Keywords: renal function; induced male; aging induced; male specific ... See more keywords
Fisetin as a caloric restriction mimetic protects rat brain against aging induced oxidative stress, apoptosis and neurodegeneration
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.11.004
Abstract: Aim: In the present study, attempts have been made to evaluate the potential role of fisetin, a caloric restriction mimetic (CRM), for neuroprotection in D‐galactose (D‐gal) induced accelerated and natural aging models of rat. Main… read more here.
Keywords: fisetin caloric; aging induced; restriction mimetic; caloric restriction ... See more keywords
Aging-induced dynamics for statically indeterminate systems.
Sign Up to like & getrecommendations! Published in 2021 at "Physical review. E"
DOI: 10.1103/physreve.104.054902
Abstract: Statically indeterminate systems are experimentally demonstrated to be in fact dynamical. Take the classic problems of a beam with three supporting points, granules in a silo, and a ladder leaning against a wall, for instance;… read more here.
Keywords: statically indeterminate; indeterminate systems; dynamics statically; aging induced ... See more keywords
Aging-Induced Recovery of Magnesium Alloys with Various Rare-Earth Metals
Sign Up to like & getrecommendations! Published in 2019 at "Russian Metallurgy (Metally)"
DOI: 10.1134/s0036029519050082
Abstract: The aging-induced recovery of binary magnesium alloys with various rare-earth metals (Y, Nd, Sm, Gd, Tb, Dy, Ho), in which the decomposition of the supersaturated magnesium solid solution is accompanied by substantial hardening, is studied.… read more here.
Keywords: rare earth; aging induced; earth metals; recovery ... See more keywords
Aging-Induced Biological Changes and Cardiovascular Diseases
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/7156435
Abstract: Aging is characterized by functional decline in homeostatic regulation and vital cellular events. This process can be linked with the development of cardiovascular diseases (CVDs). In this review, we discussed aging-induced biological alterations that are… read more here.
Keywords: induced biological; aging induced; structural biochemical; cardiovascular diseases ... See more keywords
lncRNA Xist Regulates Osteoblast Differentiation by Sponging miR-19a-3p in Aging-induced Osteoporosis.
Sign Up to like & getrecommendations! Published in 2020 at "Aging and Disease"
DOI: 10.14336/ad.2019.0724
Abstract: The switch between osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) plays a key role in aging-induced osteoporosis. In this study, miR-19a-3p was obviously downregulated in BMSCs from aged humans and mice.… read more here.
Keywords: bmscs; differentiation; lncrna xist; mir 19a ... See more keywords
NXP032 Ameliorates Aging-Induced Oxidative Stress and Cognitive Impairment in Mice through Activation of Nrf2 Signaling
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11010130
Abstract: Aging is a neurodegenerative disease that leads to cognitive impairment, and an increase in oxidative stress as a major cause is an important factor. It has been reported that aging-related cognitive impairment is associated with… read more here.
Keywords: stress; aging induced; mice; oxidative stress ... See more keywords
GSPE Pre-Treatment Exerts Long-Lasting Preventive Effects against Aging-Induced Changes in the Colonic Enterohormone Profile of Female Rats
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24097807
Abstract: The impact that healthy aging can have on society has raised great interest in understanding aging mechanisms. However, the effects this biological process may have on the gastrointestinal tract (GIT) have not yet been fully… read more here.
Keywords: female rats; enterohormone; pre treatment; treatment ... See more keywords
Leucine Supplementation in Middle-Aged Male Mice Improved Aging-Induced Vascular Remodeling and Dysfunction via Activating the Sirt1-Foxo1 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14183856
Abstract: Vascular aging is associated with metabolic remodeling, and most studies focused on fatty acid and glucose metabolism. Based on our metabolomic data, leucine was significantly reduced in the aortas of aged mice. Whether leucine supplementation… read more here.
Keywords: supplementation; leucine supplementation; male mice; vascular remodeling ... See more keywords