Aging, inflammation and cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in immunology"
DOI: 10.1016/j.smim.2018.10.011
Abstract: Aging is a key aspect of neoplasia at the level of cells, individuals and populations. Unrestrained expression and production of inflammatory mediators is a key feature of aging at the cellular and organism level. Inflammatory… read more here.
Keywords: cancer; aging inflammation; inflammation; inflammation cancer ... See more keywords
NPM1 ablation induces HSC aging and inflammation to develop myelodysplastic syndrome exacerbated by p53 loss
Sign Up to like & getrecommendations! Published in 2022 at "EMBO reports"
DOI: 10.15252/embr.202154262
Abstract: Myelodysplastic syndrome (MDS) is characterized by ineffective hematopoiesis with morphologic dysplasia and a propensity to transform into overt acute myeloid leukemia (AML). Our analysis of two cohorts of 20 MDS and 49 AML with multi‐lineage… read more here.
Keywords: loss; hsc aging; p53; aging inflammation ... See more keywords