Identification of replicative aging and inflammatory aging signatures via whole-genome CRISPRi screens
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DOI: 10.1186/s13059-025-03683-7
Abstract: Aging is a major risk factor for chronic diseases and cancer. Cellular aging, particularly in adult stem cells, offers a high-throughput framework for dissecting the molecular mechanisms of aging. We perform multiple genome-wide CRISPR interference… read more here.
Keywords: inflammatory aging; aging inflammatory; aging signatures; identification replicative ... See more keywords