Regulation of aging and oxidative stress pathways in aged pancreatic islets using alpha-lipoic acid
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-018-3363-3
Abstract: Oxidative stress has been involved in the aging process and the pathogenesis of type-2 diabetes, which is a serious health problem worldwide. This study investigates the anti-aging, anti-apoptotic, and antioxidant properties of alpha-lipoic acid (ALA),… read more here.
Keywords: oxidative stress; aging oxidative; stress; alpha lipoic ... See more keywords
Aging - Oxidative stress, antioxidants and computational modeling
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DOI: 10.1016/j.heliyon.2020.e04107
Abstract: Aging is a degenerative, biological, time-dependent, universally conserved process thus designed as one of the highest known risk factors for morbidity and mortality. Every individual has its own aging mechanisms as both environmental conditions (75%)… read more here.
Keywords: antioxidants computational; oxidative stress; computational modeling; stress antioxidants ... See more keywords
Teachings from COVID‐19 and aging ‐ an oxidative process
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DOI: 10.1111/jocd.13751
Abstract: As of June 2020, the COVID‐19 pandemic has totaled over 9 000 000 cases and 470 000 deaths globally (ref. 1). Emerging data from COVID‐19 patients have suggested a clear role for oxidative stress in… read more here.
Keywords: oxidative stress; teachings covid; covid aging; stress ... See more keywords
Hydralazine Revives Cellular and Ocular Lens Health-Span by Ameliorating the Aging and Oxidative-Dependent Loss of the Nrf2-Activated Cellular Stress Response
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DOI: 10.3390/antiox12010140
Abstract: A major hallmark of aging-associated diseases is the inability to evoke cellular defense responses. Transcriptional protein Nrf2 (nuclear factor erythroid-derived 2-related factor) plays a pivotal role in the oxidative stress response, cellular homeostasis, and health… read more here.
Keywords: health span; aging oxidative; stress response; response ... See more keywords
Female Reproductive Aging and Oxidative Stress: Mesenchymal Stem Cell Conditioned Medium as a Promising Antioxidant
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DOI: 10.3390/ijms24055053
Abstract: The recent tendency to delay pregnancy has increased the incidence of age-related infertility, as female reproductive competence decreases with aging. Along with aging, a lowered capacity of antioxidant defense causes a loss of normal function… read more here.
Keywords: cell; female reproductive; oxidative stress; reproductive aging ... See more keywords