Regulation of aging and oxidative stress pathways in aged pancreatic islets using alpha-lipoic acid
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-018-3363-3
Abstract: Oxidative stress has been involved in the aging process and the pathogenesis of type-2 diabetes, which is a serious health problem worldwide. This study investigates the anti-aging, anti-apoptotic, and antioxidant properties of alpha-lipoic acid (ALA),… read more here.
Keywords: oxidative stress; aging oxidative; stress; alpha lipoic ... See more keywords
Aging - Oxidative stress, antioxidants and computational modeling
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e04107
Abstract: Aging is a degenerative, biological, time-dependent, universally conserved process thus designed as one of the highest known risk factors for morbidity and mortality. Every individual has its own aging mechanisms as both environmental conditions (75%)… read more here.
Keywords: antioxidants computational; oxidative stress; computational modeling; stress antioxidants ... See more keywords
DNA methylation as an epigenetic mechanism in the regulation of LEDGF expression and biological response in aging and oxidative stress
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DOI: 10.1038/s41420-024-02076-2
Abstract: The physiological quantum of stress-inducible transcriptional protein, Lens Epithelium-Derived Growth Factor (LEDGF), is vital for the maintenance of cellular physiology. Erratic epigenetic reprogramming in response to oxidative stress or with advancing age is found to… read more here.
Keywords: methylation; stress; oxidative stress; response ... See more keywords
Teachings from COVID‐19 and aging ‐ an oxidative process
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DOI: 10.1111/jocd.13751
Abstract: As of June 2020, the COVID‐19 pandemic has totaled over 9 000 000 cases and 470 000 deaths globally (ref. 1). Emerging data from COVID‐19 patients have suggested a clear role for oxidative stress in… read more here.
Keywords: oxidative stress; teachings covid; covid aging; stress ... See more keywords
Hydralazine Revives Cellular and Ocular Lens Health-Span by Ameliorating the Aging and Oxidative-Dependent Loss of the Nrf2-Activated Cellular Stress Response
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DOI: 10.3390/antiox12010140
Abstract: A major hallmark of aging-associated diseases is the inability to evoke cellular defense responses. Transcriptional protein Nrf2 (nuclear factor erythroid-derived 2-related factor) plays a pivotal role in the oxidative stress response, cellular homeostasis, and health… read more here.
Keywords: health span; aging oxidative; stress response; response ... See more keywords
Female Reproductive Aging and Oxidative Stress: Mesenchymal Stem Cell Conditioned Medium as a Promising Antioxidant
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24055053
Abstract: The recent tendency to delay pregnancy has increased the incidence of age-related infertility, as female reproductive competence decreases with aging. Along with aging, a lowered capacity of antioxidant defense causes a loss of normal function… read more here.
Keywords: cell; female reproductive; oxidative stress; reproductive aging ... See more keywords