A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes
Sign Up to like & getrecommendations! Published in 2017 at "PROTEOMICS"
DOI: 10.1002/pmic.201600232
Abstract: Circulating polypeptides and proteins have been implicated in reversing or accelerating aging phenotypes, including growth/differentiation factor 8 (GDF8), GDF11, eotaxin, and oxytocin. These proteoforms, which are defined as the protein products arising from a single… read more here.
Keywords: proteomic assay; plasma; aging phenotypes; targeted proteomic ... See more keywords
Artificially stimulating retrotransposon activity increases mortality and accelerates a subset of aging phenotypes in Drosophila
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.05.23.493120
Abstract: Transposable elements (TE) are mobile sequences of DNA that can become transcriptionally active as an animal ages. Whether TE activity is simply a byproduct of heterochromatin breakdown or can contribute towards the aging process is… read more here.
Keywords: aging phenotypes; artificially stimulating; mortality; activity ... See more keywords