GWAS of epigenetic aging rates in blood reveals a critical role for TERT
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-02697-5
Abstract: DNA methylation age is an accurate biomarker of chronological age and predicts lifespan, but its underlying molecular mechanisms are unknown. In this genome-wide association study of 9907 individuals, we find gene variants mapping to five… read more here.
Keywords: epigenetic aging; age; critical role; gwas epigenetic ... See more keywords
Diverse aging rates in ectothermic tetrapods provide insights for the evolution of aging and longevity
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abm0151
Abstract: Comparative studies of mortality in the wild are necessary to understand the evolution of aging; yet, ectothermic tetrapods are underrepresented in this comparative landscape, despite their suitability for testing evolutionary hypotheses. We present a study… read more here.
Keywords: diverse aging; reptiles amphibians; evolution aging; ectothermic tetrapods ... See more keywords