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Published in 2021 at "Current opinion in ophthalmology"
DOI: 10.1097/icu.0000000000000747
Abstract: PURPOSE OF REVIEW This review explores metabolic syndrome (MetS) as a risk factor that accelerates aging in retinal neurons and may contribute to the neurodegeneration seen in glaucomatous optic neuropathy (GON) and age-related macular degeneration…
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Keywords:
metabolic syndrome;
ophthalmology;
aging retina;
syndrome aging ... See more keywords
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Published in 2021 at "Annual review of vision science"
DOI: 10.1146/annurev-vision-100419-114940
Abstract: Multifaceted and divergent manifestations across tissues and cell types have curtailed advances in deciphering the cellular events that accompany advanced age and contribute to morbidities and mortalities. Increase in human lifespan during the past century…
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Keywords:
molecular metabolic;
potential interventions;
turbulences potential;
retina molecular ... See more keywords
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Published in 2019 at "Biology"
DOI: 10.3390/biology8020031
Abstract: Mitochondria are central in retinal cell function and survival and they perform functions that are critical to cell function. Retinal neurons have high energy requirements, since large amounts of ATP are needed to generate membrane…
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Keywords:
dysfunction aging;
dysfunction;
biology;
mitochondrial dysfunction ... See more keywords