Aging, senescence and mitochondria: the PGC-1/ERR axis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-20-0196
Abstract: Aging is a degenerative process that results from the accumulation of cellular and tissue lesions, leading progressively to organ dysfunction and death. Although the biological basis of human aging remains unclear, a large amount of… read more here.
Keywords: senescence mitochondria; mitochondria pgc; pgc err; aging senescence ... See more keywords
An Aging and Senescence-Related Gene Signature for Prognosis Prediction in Clear Cell Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.871088
Abstract: Background: Clear cell renal cell carcinoma (ccRCC) is the most common solid lesion in the kidney. This study aims to establish an aging and senescence-related mRNA model for risk assessment and prognosis prediction in ccRCC… read more here.
Keywords: cell; aging senescence; prediction; risk ... See more keywords
Editorial: Premature Aging and Senescence in Renal Fibrosis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.734892
Abstract: Cellular senescence, defined as the irreversible cell cycle arrest, plays an important role in both development and disease. While acute senescence is important for organogenesis and proper wound healing, perpetuation of the senescent population is… read more here.
Keywords: fibrosis; senescence renal; senescence; disease ... See more keywords
Giant Multinucleated Cells in Aging and Senescence—An Abridgement
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11081121
Abstract: Simple Summary Aging is a progressive decline of an organism over time. In contrast, senescence occurs throughout an organism’s lifespan. It is a cell-cycle arrest preventing the proliferation of damaged cells. Cellular and molecular senescence… read more here.
Keywords: giant cells; multinucleated giant; senescent; senescence ... See more keywords