Miniaturized Forced Degradation of Therapeutic Proteins and ADCs by Agitation-Induced Aggregation using Orbital Shaking of Microplates.
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DOI: 10.1016/j.xphs.2021.09.027
Abstract: Microplate-based formulation screening is a powerful approach to identify stabilizing excipients for therapeutic proteins while reducing material requirements. However, this approach is sometimes not representative of studies conducted in relevant container closures. The present study… read more here.
Keywords: orbital shaking; induced aggregation; aggregation; therapeutic proteins ... See more keywords