Articles with "agonist 190997" as a keyword



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Potent antiproliferative activity of bradykinin B2 receptor selective agonist FR-190997 and analogue structures thereof: A paradox resolved?

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Published in 2020 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2020.112948

Abstract: Βradykinin stimulation of B2 receptor is known to activate the oncogenic ERK pathway and overexpression of bradykinin receptors B1 and B2 has been reported to occur in glioma, colorectal and cervical cancers. B1R and B2R… read more here.

Keywords: agonist 190997; antiproliferative activity; receptor; bradykinin ... See more keywords