Developing a translational murine‐to‐canine pathway for an IL‐2/agonist anti‐CD40 antibody cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary and Comparative Oncology"
DOI: 10.1111/vco.12813
Abstract: Abstract Human and canine sarcomas are difficult to treat soft tissue malignancies with an urgent need for new improved therapeutic options. Local recurrence rates for humans are between 10%–30%, and 30%–40% develop metastases. Outcomes for… read more here.
Keywords: cd40 antibody; cancer; canine; cd40 ... See more keywords
Arginase Therapy Combines Effectively with Immune Checkpoint Blockade or Agonist Anti-OX40 Immunotherapy to Control Tumor Growth
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-20-0317
Abstract: Arginine deprivation is commonly thought to be immunosuppressive. However, this study demonstrates that this is not always the case. Here, arginine deprivation in combination with different immunotherapies can enhance antitumor responses elicited by these immunotherapies.… read more here.
Keywords: arginase; combination; tumor; agonist anti ... See more keywords