PPAR Gamma Agonist Leriglitazone Recovers Alterations Due to Pank2-Deficiency in hiPS-Derived Astrocytes
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DOI: 10.3390/pharmaceutics15010202
Abstract: The novel brain-penetrant peroxisome proliferator-activated receptor gamma agonist leriglitazone, previously validated for other rare neurodegenerative diseases, is a small molecule that acts as a regulator of mitochondrial function and exerts neuroprotective, anti-oxidative and anti-inflammatory effects.… read more here.
Keywords: derived astrocytes; hips derived; gamma agonist; agonist leriglitazone ... See more keywords