TLR7/8 Agonist Loaded Nanoparticles Augment NK Cell-mediated Antibody-based Cancer Immunotherapy.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.0c00271
Abstract: Activated natural killer (NK) cells can kill malignant tumor cells via granule exocytosis and secretion of IFN-ɣ, a key regulator of TH1 response. Thus, mobilization of NK cells can augment cancer immunotherapy, particularly that mediated… read more here.
Keywords: agonist loaded; antibody; cancer immunotherapy; tlr7 agonist ... See more keywords
MP01-20 TLR7/8-AGONIST-LOADED M1-MACROPHAGE-DERIVED NANOVESICLES PROMOTE THE POLARIZATION OF MACROPHAGES TO ENHANCE BLADDER CANCER IMMUNOTHERAPY
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000815.020
Abstract: INTRODUCTION AND OBJECTIVE:Tumor-associated macrophages (TAM) are abundant in many cancers including bladder cancer, and often display an immune-suppressive M2-like phenotype to fosters tumor growt... read more here.
Keywords: bladder cancer; agonist loaded; mp01 tlr7; bladder ... See more keywords
Assessment of Efficacy and Safety Using PPAR-γ Agonist-Loaded Nanocarriers for Inflammatory Eye Diseases
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911184
Abstract: Drug-loaded nanocarriers (NCs) are new systems that can greatly improve the delivery and targeting of drugs to specific tissues and organs. In our work, a PPAR-γ agonist loaded into polymeric NCs was prepared, stabilized by… read more here.
Keywords: ppar agonist; efficacy; eye; loaded nanocarriers ... See more keywords