β2‐Adrenoceptor agonist profiling reveals biased signalling phenotypes for the β2‐adrenoceptor with possible implications for the treatment of asthma
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DOI: 10.1111/bph.15900
Abstract: β‐Adrenoceptor agonists relieve airflow obstruction by activating β2‐adrenoceptors, which are G protein‐coupled receptors (GPCRs) expressed on human airway smooth muscle (HASM) cells. The currently available β‐adrenoceptor agonists are balanced agonists, however, and signal through both… read more here.
Keywords: adrenoceptor agonist; agonist profiling; profiling reveals; asthma ... See more keywords