In-situ vaccination using focused ultrasound heating and anti-CD-40 agonistic antibody enhances T-cell mediated local and abscopal effects in murine melanoma
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Hyperthermia"
DOI: 10.1080/02656736.2019.1663280
Abstract: Abstract The success of melanoma immunotherapy is dependent on the presence of activated and functional T-cells in tumors. The objective of this study was to investigate the impact of local-focused ultrasound (FUS) heating (∼42–45 °C) and… read more here.
Keywords: melanoma; focused ultrasound; agonistic antibody; abscopal effects ... See more keywords
An Agonistic Antibody to EPHA2 Exhibits Antitumor Effects on Human Melanoma Cells
Sign Up to like & getrecommendations! Published in 2018 at "AntiCancer Research"
DOI: 10.21873/anticanres.12592
Abstract: Background/Aim: EPH receptor A2 (EPHA2) is highly expressed in aggressive types of human cancer, and is expected to be an excellent target molecule for antibody treatments. In this study, we investigated the therapeutic potential of… read more here.
Keywords: agonistic antibody; antibody; human melanoma; antibody epha2 ... See more keywords