2022 update on the scientific premise and clinical trials for IL‐15 agonists as cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.5mr0422-506r
Abstract: Diverse cytokines and their receptors on immune cells constitute a highly complex network in the immune system. Some therapeutic cytokines and their derivatives have been approved for cancer treatment. IL‐15 is an immune‐regulating cytokine with… read more here.
Keywords: 2022 update; agonists cancer; cancer immunotherapy; cancer ... See more keywords
Nanodelivery of STING agonists against cancer and infectious diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2021.101007
Abstract: Vaccination is a modality that has been widely explored for the treatment of various diseases. To increase the potency of vaccine formulations, immunostimulatory adjuvants have been regularly exploited, and the stimulator of interferon genes (STING)… read more here.
Keywords: infectious diseases; nanodelivery sting; sting agonists; cancer infectious ... See more keywords
The Role of TRL7/8 Agonists in Cancer Therapy, with Special Emphasis on Hematologic Malignancies
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DOI: 10.3390/vaccines11020277
Abstract: Toll-like receptors (TLR) belong to the pattern recognition receptors (PRR). TLR7 and the closely correlated TLR8 affiliate with toll-like receptors family, are located in endosomes. They recognize single-stranded ribonucleic acid (RNA) molecules and synthetic deoxyribonucleic… read more here.
Keywords: toll like; role; agonists cancer; therapy ... See more keywords