Articles with "agonists partial" as a keyword



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Exploring the binding energy profiles of full agonists, partial agonists, and antagonists of the α7 nicotinic acetylcholine receptor

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Published in 2017 at "Journal of Molecular Modeling"

DOI: 10.1007/s00894-017-3419-4

Abstract: Nicotinic acetylcholine receptors (nAChRs) belong to the Cys-loop receptor family and are important drug targets for the treatment of neurological diseases. However, the precise determinants of the binding efficacies of ligands for these receptors are… read more here.

Keywords: energy profiles; binding energy; agonists partial; agonists antagonists ... See more keywords