Articles with "agonists scaffold" as a keyword



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Virtual identification of novel PPARα/γ dual agonists by scaffold hopping of saroglitazar

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Published in 2018 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2017.1392363

Abstract: The thiazolidinedione class PPARγ agonists as antidiabetic agents are restricted in clinical use because of the side effects such as edema, weight gain, and heart failure. The single and selective agonism of PPARγ is the… read more here.

Keywords: ppar; ppar dual; novel ppar; scaffold hopping ... See more keywords