The Impact of Once Daily Dosing on Protein Binding of Clozapine and Norclozapine
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Psychopharmacology"
DOI: 10.1097/jcp.0000000000001979
Abstract: Abstract Purpose/Background Clozapine and norclozapine are highly protein bound. Currently, clozapine is increasingly prescribed once daily (QD). Higher (once daily) doses may theoretically lead to saturation of protein binding of (nor)clozapine, resulting in increased unbound… read more here.
Keywords: clozapine norclozapine; agp concentrations; unbound fractions; binding clozapine ... See more keywords
Cat alpha-1-acid glycoprotein enzyme-linked immunosorbent assay: performance characteristics and reference intervals
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Feline Medicine and Surgery"
DOI: 10.1177/1098612x231162836
Abstract: Objectives The aim of this study was to evaluate performance of a feline-specific ELISA for the measurement of alpha-1-acid glycoprotein (AGP) and to establish a reference interval (RI). Methods Surplus serum samples with low (~200 µg/ml),… read more here.
Keywords: acid glycoprotein; alpha acid; performance; agp concentrations ... See more keywords