Articles with "agr" as a keyword



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Preoperative albumin‐to‐globulin ratio predicts survival in patients with non‐small‐cell lung cancer after surgery

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.26766

Abstract: The prognostic value of the preoperative albumin‐to‐globulin ratio (AGR) has not been investigated in non‐small‐cell lung cancer (NSCLC). Therefore, we aimed to assess the clinical applicability of the preoperative AGR to predict the prognosis in… read more here.

Keywords: surgery; agr; preoperative agr; albumin globulin ... See more keywords

PASylated interferon &agr; efficiently suppresses hepatitis B virus and induces anti‐HBs seroconversion in HBV‐transgenic mice

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Published in 2019 at "Antiviral Research"

DOI: 10.1016/j.antiviral.2018.11.003

Abstract: ABSTRACT Interferon &agr; (IFN&agr;) so far is the only therapeutic option for chronic hepatitis B virus (HBV) infection that can lead to virus clearance. Unfortunately, its application is limited by side effects and response rates… read more here.

Keywords: agr; hbv transgenic; ifn agr; mifn agr ... See more keywords
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Blockade of nicotinic acetylcholine receptor enhances the responsiveness to bupropion in the mouse forced swim test

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Published in 2019 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2018.12.027

Abstract: HIGHLIGHTSRole of nicotinic receptors was tested in the antidepressant effects of bupropion.&agr;4, &agr;5, &agr;6, and &bgr;2 nicotinic receptor subunit WT&KO mice were studied using the FST.&agr;4, &agr;6, and &bgr;2 subunits modulate the antidepressant‐like effects of… read more here.

Keywords: agr bgr; agr; mice; agr agr ... See more keywords
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Prognostic Value of Pretreatment Albumin‐to‐Globulin Ratio in Patients With Non–Muscle‐Invasive Bladder Cancer

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Published in 2018 at "Clinical Genitourinary Cancer"

DOI: 10.1016/j.clgc.2017.12.013

Abstract: &NA; In an investigation of the relationship between albumin‐to‐globulin ratio (AGR) and oncologic outcomes in 364 non–muscle‐invasive bladder cancer (NMIBC) patients, those with AGR < 1.6 had significantly poorer recurrence‐free and progression‐free survival than those… read more here.

Keywords: pretreatment agr; agr; recurrence; muscle invasive ... See more keywords
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Evolution of Ciona intestinalis Tumor necrosis factor alpha (CiTNF&agr;): Polymorphism, tissues expression, and 3D modeling

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Published in 2017 at "Developmental and Comparative Immunology"

DOI: 10.1016/j.dci.2016.11.005

Abstract: ABSTRACT Although the Tumor necrosis factor gene superfamily seems to be very conserved in vertebrates, phylogeny, tissue expression, genomic and gene organization, protein domains and polymorphism analyses showed that a strong change has happened mostly… read more here.

Keywords: agr; citnf agr; tumor necrosis; necrosis factor ... See more keywords
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Pigment epithelium‐derived factor improves TNF&agr;‐induced hepatic steatosis in grass carp (Ctenopharyngodon idella)

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Published in 2017 at "Developmental and Comparative Immunology"

DOI: 10.1016/j.dci.2017.01.016

Abstract: ABSTRACT Pro‐inflammatory cytokines, such as tumor necrosis factor alpha (TNF&agr;), may contribute to hepatic steatosis in the situation of excess lipid accumulation in farmed fish. Pigment epithelium‐derived factor (PEDF) is an endogenous anti‐inflammatory factor and… read more here.

Keywords: hepatic steatosis; agr; tnf agr; grass carp ... See more keywords
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Characterization, functional and signaling elucidation of pigeon (Columba livia) interferon‐&agr;: Knockdown p53 negatively modulates antiviral response

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Published in 2019 at "Developmental and Comparative Immunology"

DOI: 10.1016/j.dci.2018.08.017

Abstract: ABSTRACT The regulation of interferon‐&agr; signaling pathways is essential to protect the host from infection with a broad range of viruses. However, information regarding antiviral response and the specific molecular mechanism of Columba livia interferon‐&agr;… read more here.

Keywords: agr; coifn agr; antiviral response; columba livia ... See more keywords
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Inhibition of estrogen related receptor &agr; attenuates vascular smooth muscle cell proliferation and migration by regulating RhoA/p27Kip1 and &bgr;‐Catenin/Wnt4 signaling pathway

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Published in 2017 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.02.020

Abstract: Abstract RhoA/p27Kip1 and &bgr;‐Catenin/Wnt4 signaling processes play central roles in proliferation and migration in vascular smooth muscle cells (VSMCs). ERR&agr;, a member of orphan nuclear receptors, is a potent prognostic factor in breast, ovarian, colon… read more here.

Keywords: agr; proliferation; migration; err agr ... See more keywords

Endothelium‐derived hyperpolarizing factor and protein kinase G I&agr; activation: H2O2 versus S‐nitrosothiols

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Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2018.03.019

Abstract: Abstract Protein kinase G (PKG) I&agr; mediates the cyclic guanosine monophosphate‐mediated vasodilatory effects induced by NO. Endothelium‐derived hyperpolarizing factors (EDHFs), like H2O2 can activate PKGI&agr; in a cyclic guanosine monophosphate‐independent manner, but whether this is… read more here.

Keywords: pkgi agr; agr; h2o2; activation ... See more keywords
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Resveratrol attenuates high fat diet‐induced mouse cardiomyopathy through upregulation of estrogen related receptor‐&agr;

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Published in 2019 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2018.10.018

Abstract: ABSTRACT Resveratrol reportedly promotes the improvement of cardiac dysfunction and other cardiovascular diseases. Studies demonstrate resveratrol exhibits a set of benefits, including anti‐oxidative property, anti‐apoptosis and anti‐inflammation. However, the molecular mediators of resveratrol‐induced cardiac benefits… read more here.

Keywords: resveratrol; agr; err agr; related receptor ... See more keywords
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Impact of DHA intake in a mouse model of synucleinopathy

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Published in 2018 at "Experimental Neurology"

DOI: 10.1016/j.expneurol.2017.12.002

Abstract: ABSTRACT Polyunsaturated fatty acids omega‐3 (n‐3 PUFA), such as docosahexaenoic acid (DHA), have been shown to prevent, and partially reverse, neurotoxin‐induced nigrostriatal denervation in animal models of Parkinson's disease (PD). However, the accumulation of &agr;‐synuclein… read more here.

Keywords: agr; thy1 agr; mice; agr syn ... See more keywords