The absence of SIRT3 and SIRT5 promotes the acetylation of lens proteins and improves the chaperone activity of &agr;‐crystallin in mouse lenses
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DOI: 10.1016/j.exer.2019.02.024
Abstract: Abstract Acetylation of lysine residues occurs in lens proteins. Previous studies have shown an improvement in the chaperone activity of &agr;A‐crystallin upon acetylation. Sirtuins are NAD+‐dependent enzymes that can deacylate proteins. The roles of sirtuins… read more here.
Keywords: agr crystallin; mouse lenses; acetylation; sirt3 sirt5 ... See more keywords