Nutrient-sensing nuclear receptors PPAR&agr; and FXR control liver energy balance
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DOI: 10.1172/jci88893
Abstract: The nuclear receptors PPAR&agr; (encoded by NR1C1) and farnesoid X receptor (FXR, encoded by NR1H4) are activated in the liver in the fasted and fed state, respectively. PPAR&agr; activation induces fatty acid oxidation, while FXR… read more here.
Keywords: liver energy; nuclear receptors; ppar agr; agr fxr ... See more keywords