CCCTC‐Binding Factor Translates Interleukin 2‐ and &agr;‐Ketoglutarate‐Sensitive Metabolic Changes in T Cells into Context‐Dependent Gene Programs
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DOI: 10.1016/j.immuni.2017.07.015
Abstract: &NA; Despite considerable research connecting cellular metabolism with differentiation decisions, the underlying mechanisms that translate metabolite‐sensitive activities into unique gene programs are still unclear. We found that aspects of the interleukin‐2 (IL‐2)‐sensitive effector gene program… read more here.
Keywords: sensitive metabolic; gene programs; metabolic changes; agr sensitive ... See more keywords