Leukopenie mit unklarem Fieber
Sign Up to like & getrecommendations! Published in 2017 at "Der Internist"
DOI: 10.1007/s00108-017-0207-2
Abstract: ZusammenfassungWir berichten über einen 77-jährigen Patienten mit neutropenischem Fieber bei einer neu aufgetretenen Agranulozytose. Anamnestisch konnte die Einnahme von Metamizol als Auslöser der Agranulozytose gesichert werden. Die Knochenmarkpunktion konnte die Diagnose einer metamizolinduzierten Agranulozytose als… read more here.
Keywords: mit unklarem; der; agranulocytosis; mit ... See more keywords
Decreased miR-17-92 cluster expression level in serum and granulocytes preceding onset of antithyroid drug-induced agranulocytosis
Sign Up to like & getrecommendations! Published in 2017 at "Endocrine"
DOI: 10.1007/s12020-017-1481-4
Abstract: PurposeWe aimed to determine changes in miR-17-92 cluster expression in serum and granulocytes from patients with antithyroid drug (ATD)-induced agranulocytosis.MethodsIn this study, real-time polymerase chain reaction (PCR) was used to detect serum miR-17-92 expression levels… read more here.
Keywords: induced agranulocytosis; mir cluster; serum granulocytes; expression ... See more keywords
Emphasis on the early diagnosis of antithyroid drug-induced agranulocytosis: retrospective analysis over 16 years at one Chinese center
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-017-0626-x
Abstract: PurposeAntithyroid drug (ATD)-induced agranulocytosis is a rare but life-threatening adverse drug reaction that occurs in patients during the treatment of Graves’ disease. We aimed to comprehensively examine data for patients with this rare complication and… read more here.
Keywords: induced agranulocytosis; diagnosis; early diagnosis; drug ... See more keywords
SU93 REPLICATION OF TWO INDEPENDENT LOCI IN HLA-DQB1 AND HLA-B CONTRIBUTING TO THE RISK OF CLOZAPINE-INDUCED AGRANULOCYTOSIS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.282
Abstract: Background The atypical antipsychotic drug clozapine is the only effective drug for treatment-resistant schizophrenia, but also bears the risk of inducing severe adverse drug responses like neutropenia and agranulocytosis. Agranulocytosis and neutropenia occurs in about… read more here.
Keywords: clozapine; induced agranulocytosis; hla dqb1; clozapine induced ... See more keywords
Association of HLA-B and HLA-DRB1 polymorphisms with antithyroid drug-induced agranulocytosis in a Han population from northern China
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12350-2
Abstract: Antithyroid drug (ATD)-induced agranulocytosis is associated with human leukocyte antigen (HLA) and nearby genes in Southeast Asian and European populations. The susceptibility of the Han population from northern China to ATD-induced agranulocytosis has not been… read more here.
Keywords: induced agranulocytosis; hla drb1; hla; hla hla ... See more keywords
Should Patients' Values Be Discussed in Relation to Long-Term Blood Monitoring Before and During Clozapine Treatment?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Psychopharmacology"
DOI: 10.1097/jcp.0000000000001233
Abstract: To the Editors: C lozapine is the only antipsychotic medication that is indicated for use in treatment-resistant schizophrenia (TRS), which has an estimated prevalence of 20% to 30%. The true level of TRSmay be lower… read more here.
Keywords: blood monitoring; clozapine; treatment; clozapine treatment ... See more keywords
Agranulocytosis Associated with Waldenström Macroglobulinemia
Sign Up to like & getrecommendations! Published in 2018 at "Acta Haematologica"
DOI: 10.1159/000489482
Abstract: Currently, there are only 2 case reports of Waldenström macroglobulinemia (WM) associated with severe neutropenia. This is a case report of a woman with a past medical history of WM who presented with neutropenic fever.… read more here.
Keywords: waldenstr macroglobulinemia; associated waldenstr; case; agranulocytosis ... See more keywords
Agranulocytosis Induced by Tamoxifen in a Breast Cancer Patient
Sign Up to like & getrecommendations! Published in 2019 at "Breast Care"
DOI: 10.1159/000500708
Abstract: Background: The main side effects of tamoxifen are menopausal symptoms. We report a case of agranulocytosis induced by tamoxifen in a 33-year-old woman treated in the adjuvant setting. Case Presentation: Ten days after the beginning… read more here.
Keywords: agranulocytosis induced; breast cancer; induced tamoxifen; agranulocytosis ... See more keywords
Concurrent severe hepatotoxicity and agranulocytosis induced by Polygonum multiflorum: A case report
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v10.i27.9921
Abstract: BACKGROUND Various types of drug-induced liver injury are induced by Polygonum multiflorum (PM); however, it rarely causes neutropenia. Herein, we report the case of a 65-year-old woman with concurrent severe hepatotoxicity and agranulocytosis induced by… read more here.
Keywords: hepatotoxicity agranulocytosis; hepatotoxicity; induced polygonum; case ... See more keywords
Chemotherapy-related agranulocytosis as a predictive factor for germline BRCA1 pathogenic variants in breast cancer patients: a retrospective cohort study.
Sign Up to like & getrecommendations! Published in 2023 at "Swiss medical weekly"
DOI: 10.57187/smw.2023.40055
Abstract: BACKGROUND Carriers of germline pathogenic variants of the BRCA1 gene (gBRCA1) tend to have a higher incidence of haematological toxicity upon exposure to chemotherapy. We hypothesised that the occurrence of agranulocytosis during the first cycle of (neo-)adjuvant… read more here.
Keywords: pathogenic variants; first cycle; breast cancer; agranulocytosis ... See more keywords