The extracellular matrix protein Agrin is expressed by osteoblasts and contributes to their differentiation.
Sign Up to like & getrecommendations! Published in 2021 at "Cell and tissue research"
DOI: 10.1007/s00441-021-03494-9
Abstract: The extracellular matrix protein Agrin has been detected in chondrocytes and endosteal osteoblasts but its function in osteoblast differentiation has not been investigated yet. Thus, it is possible that Agrin contributes to osteoblast differentiation and,… read more here.
Keywords: matrix protein; agrin; extracellular matrix; differentiation ... See more keywords
MYO9A deficiency in motor neurons is associated with reduced neuromuscular agrin secretion
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DOI: 10.1093/hmg/ddy054
Abstract: Abstract Congenital myasthenic syndromes (CMS) are a group of rare, inherited disorders characterized by compromised function of the neuromuscular junction, manifesting with fatigable muscle weakness. Mutations in MYO9A were previously identified as causative for CMS… read more here.
Keywords: secretion; agrin; intracellular transport; motor ... See more keywords
Determination of Agrin and Related Proteins Levels as a Function of Age in Human Hearts
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DOI: 10.3389/fcvm.2022.813904
Abstract: Background: Mature cardiomyocytes are unable to proliferate, preventing the injured adult heart from repairing itself. Studies in rodents have suggested that the extracellular matrix protein agrin promotes cardiomyocyte proliferation in the developing heart and that… read more here.
Keywords: age human; determination agrin; age; heart ... See more keywords
Neuronal Agrin Promotes Proliferation of Primary Human Myoblasts in an Age-Dependent Manner
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DOI: 10.3390/ijms231911784
Abstract: Neuronal agrin, a heparan sulphate proteoglycan secreted by the α-motor neurons, promotes the formation and maintenance of the neuromuscular junction by binding to Lrp4 and activating muscle-specific kinase (MuSK). Neuronal agrin also promotes myogenesis by… read more here.
Keywords: age dependent; human myoblasts; proliferation; neuronal agrin ... See more keywords