[6]‐Gingerol–induced cell cycle arrest, reactive oxygen species generation, and disruption of mitochondrial membrane potential are associated with apoptosis in human gastric cancer (AGS) cells
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DOI: 10.1002/jbt.22206
Abstract: Ginger (Zingiber officinale Roscoe), a monocotyledonous herb, is widely used as an herbal medicine owing to the phytoconstituents it possesses. In the current study, the quantity of [6]‐gingerol, the major phenolic ketone, in the fresh… read more here.
Keywords: reactive oxygen; oxygen species; gingerol; human gastric ... See more keywords
Curcuma wenyujin Y. H. Chen et C. Ling n-Butyl alcohol extract inhibits AGS cell Helicobacter pyloriCagA+VacA+ promoted invasiveness by down-regulating caudal type homeobox transcription factor and claudin-2 expression
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DOI: 10.1007/s11655-017-2958-y
Abstract: ObjectiveTo investigate the effects and possible mechanisms of action of Curcuma wenyujin Y. H. Chen et C. Ling n-Butyl alcohol extract (CWNAE) on repression of human gastric cancer (GC) AGS cell invasion induced by co-culturing… read more here.
Keywords: vaca; group; expression; hpcaga vaca ... See more keywords
Synthesis of 8-Fluoroneocryptolepine and Evaluation for Cytotoxic Activity against AGS Cancer Cells.
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DOI: 10.1021/acs.jnatprod.1c01078
Abstract: Neocryptolepine derivatives have attracted great interest because of their unique cytotoxic activity. 8-Fluoroneocryptolepine (8FNC) was synthesized, and its cytotoxicity was evaluated by MTT assay in AGS gastric cancer cells and gastric mucosa GES-1 cells. 8-Fluoroneocryptolepine… read more here.
Keywords: cancer; cytotoxic activity; ags cells; gastric cancer ... See more keywords
Effects of natural phenolic compound carvacrol on the human gastric adenocarcinoma (AGS) cells in vitro
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DOI: 10.1097/cad.0000000000000491
Abstract: Gastric cancer (GC) is the most common cause of morbidity and mortality because of cancer. Medicinal plants containing polyphenolic compounds have gained importance in anticancer treatment. In this context, carvacrol is a main component of… read more here.
Keywords: gastric adenocarcinoma; adenocarcinoma ags; human gastric; carvacrol ... See more keywords
Helicobacter pylori enhances HLA‐C expression in the human gastric adenocarcinoma cells AGS and can protect them from the cytotoxicity of natural killer cells
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DOI: 10.1111/hel.13069
Abstract: Helicobacter pylori (H. pylori) seems to play causative roles in gastric cancers. H. pylori has also been detected in established gastric cancers. How the presence of H. pylori modulates immune response to the cancer is… read more here.
Keywords: surface expression; cytotoxicity; pylori; ags cells ... See more keywords
Abstract 5840: Normal fibroblasts, cancer-associated fibroblasts, and their senescent counterparts exert varying effects on tumorigenic potential and ABT-263 sensitivity of gastric cancer cells
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DOI: 10.1158/1538-7445.am2023-5840
Abstract: It has become increasingly apparent that cancer is not a tumor cell-centric disease. Elements of the tumor microenvironment (TME), including fibroblasts and senescent cells, have been shown to contribute to tumor cell proliferation, metastasis, and… read more here.
Keywords: abt 263; sensitivity; ags cells; fibroblasts senescent ... See more keywords
Abstract 5965: First-in-class chemical induced proximity system achieves dose-dependent control of TP53 activation in gastric cancer
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DOI: 10.1158/1538-7445.am2024-5965
Abstract: Background: Gastric cancer (GC) remains a common and deadly disease, and inactivating TP53 mutations occur in up to 68% of GC tumors. p53 is a master regulator of multiple cellular pathways, such as the cell… read more here.
Keywords: cancer; system; chemical; gastric cancer ... See more keywords
Exopolysaccharide from Lactiplantibacillus plantarum YT013 and Its Apoptotic Activity on Gastric Cancer AGS Cells
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DOI: 10.3390/fermentation9060539
Abstract: Cancer is a significant health burden in the world. Natural product drugs have received widespread attention because of their safety and effectiveness, stable effects and fewer side effects. Some studies have demonstrated that exopolysaccharide (EPS)… read more here.
Keywords: plantarum yt013; ags cells; gastric cancer; lactiplantibacillus plantarum ... See more keywords
The Effects of Sulglycotide on the Adhesion and the Inflammation of Helicobacter Pylori
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DOI: 10.3390/ijerph17082918
Abstract: Helicobacter pylori (H. pylori) is a primary etiologic factor in gastric diseases. Sulglycotide is a glycopeptide derived from pig duodenal mucin. Esterification of its carbohydrate chains with sulfate groups creates a potent gastroprotective agent used… read more here.
Keywords: adhesion inflammation; adhesion; effects sulglycotide; ags cells ... See more keywords
Outer Membrane Vesicle Production by Helicobacter pylori Represents an Approach for the Delivery of Virulence Factors CagA, VacA and UreA into Human Gastric Adenocarcinoma (AGS) Cells
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DOI: 10.3390/ijms22083942
Abstract: Helicobacter pylori infection is the etiology of several gastric-related diseases including gastric cancer. Cytotoxin associated gene A (CagA), vacuolating cytotoxin A (VacA) and α-subunit of urease (UreA) are three major virulence factors of H. pylori,… read more here.
Keywords: caga vaca; vaca urea; virulence factors; ags cells ... See more keywords
TNF−α Secreted from Macrophages Increases the Expression of Prometastatic Integrin αV in Gastric Cancer
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DOI: 10.3390/ijms24010376
Abstract: The tumor microenvironment comprising blood vessels, fibroblasts, immune cells, and the extracellular matrix surrounding cancer cells, has recently been targeted for research in cancer therapy. We aimed to investigate the effect of macrophages on the… read more here.
Keywords: ags cells; integrin; expression; gastric cancer ... See more keywords