High-speed AFM reveals accelerated binding of agitoxin-2 to a K+ channel by induced fit
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DOI: 10.1126/sciadv.aax0495
Abstract: We revealed that binding of agitoxin-2 to a K+ channel uses an induced-fit pathway by single-molecule analysis via high-speed AFM. Agitoxin-2 (AgTx2) from scorpion venom is a potent blocker of K+ channels. The docking model… read more here.
Keywords: agitoxin; channel; induced fit; agtx2 ... See more keywords