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Published in 2017 at "Marine pollution bulletin"
DOI: 10.1016/j.marpolbul.2016.10.064
Abstract: A total of 9 sediment samples of Liaohe River protected areas were collected to evaluate aryl hydrocarbon receptor agonists (AhR-agonists) and AhR-agonist activity via chemical analysis and in vitro H4IIE cell bioassay. Results indicated that…
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Keywords:
protected areas;
river protected;
ahr agonist;
liaohe river ... See more keywords
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Published in 2020 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2020.08.008
Abstract: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is highly expressed in placenta. AhR belongs to a class of transcriptional regulators that control many developmental and physiological events (e.g. xenobiotic metabolism). Our…
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Keywords:
ahr agonist;
hydrocarbon receptor;
aryl hydrocarbon;
human primary ... See more keywords
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Published in 2022 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.2c00956
Abstract: Identification and analysis of small molecule bioactivity in target-agnostic cellular assays and monitoring changes in phenotype followed by identification of the biological target are a powerful approach for the identification of novel bioactive chemical matter…
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Keywords:
highly potent;
potent ahr;
ahr agonist;
identification ... See more keywords