Baicalein ameliorates ulcerative colitis by improving intestinal epithelial barrier via AhR/IL-22 pathway in ILC3s.
Sign Up to like & getrecommendations! Published in 2021 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-021-00781-7
Abstract: Ulcerative colitis (UC) is a chronic inflammatory disease of the gastrointestinal tract, which is closely related to gut barrier dysfunction. Emerging evidence shows that interleukin-22 (IL-22) derived from group 3 innate lymphoid cells (ILC3s) confers… read more here.
Keywords: barrier; baicalein ameliorates; colitis; ulcerative colitis ... See more keywords
A CRISPR/Cas9 Whole-Genome Screen Identifies Genes Required for Aryl Hydrocarbon Receptor-Dependent Induction of Functional CYP1A1
Sign Up to like & getrecommendations! Published in 2019 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfz111
Abstract: Abstract Environmental pollutants including halogenated aromatic hydrocarbons and polycyclic aromatic hydrocarbons, including benzo[a]pyrene, exert their deleterious effects through the activation of the aryl hydrocarbon receptor (AHR) and by the resulting transcription of genes not yet… read more here.
Keywords: crispr cas9; hydrocarbon receptor; aryl hydrocarbon; cyp1a1 ... See more keywords