AHR signaling in the development and function of intestinal immune cells and beyond
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-018-0694-9
Abstract: The intestinal immune system is challenged daily with the task of recognizing and eliminating pathogens while simultaneously tolerating dietary and commensal antigens. All components must effectively coordinate to differentiate a continual barrage of environmental cues… read more here.
Keywords: ahr signaling; intestinal immune; function; immune cells ... See more keywords
The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.11.055
Abstract: Zebrafish have a high capacity to replace lost neurons after brain injury. New neurons involved in repair are generated by a specific set of glial cells, known as ependymoglial cells. We analyze changes in the… read more here.
Keywords: ahr signaling; neurogenesis; hydrocarbon receptor; aryl hydrocarbon ... See more keywords
Role of the aryl hydrocarbon receptor (AhR) signaling pathway in exceptional longevity in humans
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.361
Abstract: Centenarians are the best example of successfully aging in humans. Thus, the characterization of the biological processes and pathways in this population is an excellent strategy to understand the lifespan extension. The aryl hydrocarbon receptor… read more here.
Keywords: ahr signaling; longevity; hydrocarbon receptor; aryl hydrocarbon ... See more keywords
Aryl hydrocarbon receptor signaling activation in systemic sclerosis attenuates collagen production and is a potential antifibrotic target.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106886
Abstract: Systemic sclerosis (SSc) is a systemic autoimmune disease that often leads to fibrosis of multiple organs, and there are no effective treatments. Aryl hydrocarbon receptor (AhR) is a highly evolutionarily conserved transcription factor activated by… read more here.
Keywords: ahr signaling; hydrocarbon receptor; aryl hydrocarbon; systemic sclerosis ... See more keywords
Corrigendum to “Perillaldehyde Inhibits AHR Signaling and Activates NRF2 Antioxidant Pathway in Human Keratinocytes”
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/6091947
Abstract: [This corrects the article DOI: 10.1155/2018/9524657.]. read more here.
Keywords: ahr signaling; perillaldehyde inhibits; signaling activates; corrigendum perillaldehyde ... See more keywords
The AHR Signaling Attenuates Autoimmune Responses During the Development of Type 1 Diabetes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01510
Abstract: The aryl hydrocarbon receptor (AHR) is a ligand-activated transcriptional factor widely expressed in immune cells. Its ligands range from xenobiotics and natural substances to metabolites, which renders it capable of sensing and responding to a… read more here.
Keywords: ahr signaling; attenuates autoimmune; autoimmune responses; type diabetes ... See more keywords
Gut Microbiota Regulation of AHR Signaling in Liver Disease
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12091244
Abstract: Liver health plays a vital role in human health and disease. Emerging evidence has shown the importance of the aryl hydrocarbon receptor (AHR) in liver diseases such as alcoholic liver disease, fatty liver disease, and… read more here.
Keywords: disease; liver disease; ahr signaling; gut microbiota ... See more keywords